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Mapt

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Compare Product Name Species Source
  • HY-P700423
    Tau/MAPT Protein, Macaca mulatta (HEK293, His)

    Mapt; TAU; MSTD; PPND; DDPAC; MaptL; MTBT1; MTBT2; FTDP-17; microtubule-associated protein tau; microtubule-associated protein tau; PHF-tau; paired helical filament-tau; neurofibrillary tangle protein; microtubule-associated protein tau, isoform 4; G protein beta1/gamma2 subunit-interacting factor 1

    		 Rhesus Macaque HEK293
    Tau/MAPT Protein crucially promotes microtubule assembly and stability, essential for neuronal polarity. Structurally, its C-terminus binds axonal microtubules, and the N-terminus engages neural plasma membrane components, suggesting a role as a linker protein connecting microtubules to the plasma membrane. Tau's localization dictates axonal polarity, particularly near the centrosome. Short isoforms offer cytoskeletal plasticity, while longer isoforms stabilize microtubules. Tau interacts with proteins like MARK1, MARK2, SQSTM1, and LRP1, revealing its multifaceted role in cellular processes. Tau/MAPT Protein, Macaca mulatta (HEK293, His) is the recombinant Rhesus Macaque-derived Tau/MAPT protein, expressed by HEK293, with N-10*His labeled tag. The total length of Tau/MAPT Protein, Macaca mulatta (HEK293, His) is 458 a.a., with molecular weight of 50.6 kDa.

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